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#BS-2022-MERE35-6A712022 Mercedes-Benz E 350Problems, Recalls & Reliability
Based on reports from 12 owners and 3 recalls for this exact model.
Data updated ·NHTSA complaints through October 19, 2026
Preliminary Verdict
Green Light
Based on 12 complaints, 0 crashes, 0 fires, and 3 recalls.
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Mechanic Inspection Checklist
2 owners reported collision avoidance issues — failures commonly reported around 14K miles.
30,000-Mile Cost Projection
Best Case
Most Likely
Worst Case
Top cost driver: Collision Avoidance (2 reports).
Also in your report
Owner Intelligence
AI-synthesized themes from real complaints
Buyer Lot Checklist
Questions, test drive checks, walk-away triggers
Negotiation Talking Points
Data-backed dollar deductions
Buy / Skip Verdict
Final recommendation with conditions
Where the complaints fall
2022 Mercedes-Benz E 350: Known Issues & Problem Areas
Collision Avoidance Issues
Collision Avoidance complaints account for 17% of all reports filed for the 2022 Mercedes-Benz E 350, with 2 owners filing complaints with NHTSA. The median mileage at time of complaint is 14,403 miles, suggesting issues tend to surface around the 14K-mile mark.
Electrical Issues
Electrical complaints account for 8% of all reports filed for the 2022 Mercedes-Benz E 350, with 1 owners filing complaints with NHTSA. Owners should pay attention to electrical-related symptoms during test drives and pre-purchase inspections.
Forward Collision Avoidance: Adaptive Cruise Control Issues
Forward Collision Avoidance: Adaptive Cruise Control complaints account for 8% of all reports filed for the 2022 Mercedes-Benz E 350, with 1 owners filing complaints with NHTSA. Owners should pay attention to forward collision avoidance: adaptive cruise control-related symptoms during test drives and pre-purchase inspections.
Forward Collision Avoidance: Automatic Emergency Braking Issues
Forward Collision Avoidance: Automatic Emergency Braking complaints account for 8% of all reports filed for the 2022 Mercedes-Benz E 350, with 1 owners filing complaints with NHTSA. Owners should pay attention to forward collision avoidance: automatic emergency braking-related symptoms during test drives and pre-purchase inspections.
Data sourced from NHTSA owner complaints and community reports. The full report analyzes severity, repair costs, and failure patterns for each category.
Complaint trend by year
Complaints filed with NHTSA by year for the 2022 Mercedes-Benz E 350. Recent trend: increasing.



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Recall History (3 recalls)
STEERING: STEERING WHEEL/HANDLE BAR
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.
FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.
Recall severity analysis & seller scripts
The full report rates each recall's severity and gives you scripts for asking the seller about recall completion.
About this data
NHTSA Complaints
Federal database of owner-filed safety complaints. 12 records for this vehicle.
NHTSA Recalls
Manufacturer-issued safety recalls. 3 recalls found for this vehicle.
Repair Cost Data
Real-world repair costs from owner reports and independent databases.
Last updated . NHTSA complaints received through October 19, 2026.
Other Mercedes-Benz E 350 Model Years
View all Mercedes-Benz E 350 years →2022 Mercedes-Benz E 350: Frequently Asked Questions
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What mileage do Mercedes-Benz E 350 problems start?
When was the 2022 Mercedes-Benz E 350 data last updated?
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10 sections of AI analysis based on 12 owner reports. Know before you buy.